|
Contraindicated.
These drugs should not be used during lactation.
If they are essential to the mother's health, breast-feeding
should be discontinued temporarily or permanently.
|
| |
|
|
| Amantadine** |
Cocaine |
Iodide
(including topical forms) |
| Aminodarone |
Dipyrone
(in Mexican drugs) |
Metamizol
(same as dipyrone) |
| Antineoplastic
agents |
Gold
salts |
Radiopharmaceuticals
(withhold breastfeeding temporarily) |
| Bromide |
Indandione
anticoagulants (eg, phenindione) |
Salicylates
(large doses) |
| Chloramphenicol*** |
|
|
| |
|
|
| Potentially
Hazardous. Although not generally contraindicated,
these agents should be used with caution and avoided if
possible, particularly while breast-feeding a newborn. |
| |
|
|
| Acebutolol |
Doxepin |
Nicotine/Smoking** |
| Alcohol
(especially large amounts) |
Ergotamine |
Nitrofurantoin |
| Antihistamine/Decongestant
combinations** |
Ethosuximide |
Phenobarbital
(anticonvulsant dose) |
| Atenolol |
Fluorescein |
Piroxicam |
| Benzodiazepines
(lorazepam, oxazepam preferred) |
Fluoxetine |
Primidone |
| Chlorthalidone** |
Lindane |
Quinolone
antibacterials (norfloxacin preferred) |
| Clindamycin |
Lithium |
Reserpine |
| Clonidine** |
Methimazole |
Sotalol |
| Contraceptives,
estrogen-containing** |
Nadolol |
Sulfonamides,
long-acting |
| Cyclosporine |
Narcotics
(in addicts or with therapeutic doses in first 10 days
postpartum) |
Thiazide
diuretics, long-acting or high doses** |
| Diazepam |
Metronidazole*** |
|
| |
|
|
| Probably
Safe in Usual Doses. Data are insufficient to ensure
that these agents have no adverse effects in breast-feeding
infants; if these effects occur, they probably are infrequent
or mild. There is a potential for rare allergic or idiosyncratic
reactions. |
| |
|
|
| ACE
inhibitors (eg, enalapril) |
Decongestants,
oral** |
Propylthioracil |
| Aminoglycoside
antibiotics |
Ergonovine
(short courses)** |
Quinidine |
| Anticholinergic
agents |
Fluconazole |
Salicylates
(occasional use) |
| Anticonvulsants
(except ethosuximide and phenobarbital) |
Histamine
H2-receptor antagonists (famotidine preferred) |
Spironolactone |
| Antidepressants
(except diazepam) |
Isoniazid
|
Sulfisoxazole |
| Antihistamines |
Levothyroxide |
Terfenadine |
| Antitubercular
agents |
Metoclopramide
(10 to 14 days) |
Tetracyclines
(2 weeks or less) |
| Azathiopine
(immunosuppression following organ transplant) |
Nonsteroidal
anti-inflammatory agents (ibuprofen preferred) |
Thiazide
diuretics, short-acting (low doses) |
| Barbiturates
(except phenobarbital) |
Oxazepam |
Tricyclic
antidepressants (nortriptyline, desipramine preferred;
avoid doxepin) |
| Butyrophenones
(eg, haloperidol) |
Phenothiazines |
Verapamil |
| |
|
|
| Safe
in Usual Doses. Although the potential for rare allergic
or idiosyncratic reactions should be kept in mind, usual
doses pose little risk for the breasfed infant. |
| |
|
|
| Acetaminophen |
Flurbiprofen |
Metoprolol |
| Antacids |
Heparin |
Miconazole |
| Caffeine |
Inhalers,
bronchodilators, corticosteroids |
Pencillins |
| Cephalosporins |
Insulin |
Propranolol |
| Clotrimazole |
Labetalol |
Theophylline |
| Contraceptives,
progestin only |
Laxatives,
bulk-forming and stool softening (eg, psyllium, docusate) |
Thyroid
replacement |
| Corticosteroids |
Lidocaine |
Vaccines |
| Decongestant
nasal sprays |
Magnesium
sulfate |
Vancomycin |
| Digoxin |
Methyldopa |
Warfarin |
| Erythromycin |
Methylergonovine
(short courses) |
|
| |
|
|
| *Compiled
by Philip Anderson, PharmD, Director, Drug Information
Service, University of California, San Diego, CA |
| **Drug
also may inhibit lactation. |
| ***In
situations where bottle feeding threatens the infant's
life, breastfeeding may be undertaken cautiosly. |
| Sources:
Knoben JE, Anderson PO. Handbook of Clinical Drug Data.
7th ed. Hamilton Press; 1993; Anderson P. Drug use during
breastfeeding. Clin Pharm. 1991;10:596-624; UCSD Drug
Information Service. |
| Note:
The information contained in this table is time-limited.
It is current and accurate as of 9/95. For use beyond
that date, review and updating may be necessary. |
| Used
with permission. |
