ibabydoc - Decrease in Disease Morbidity in 1998 from 20th Century Average

Decrease in Disease Morbidity in 1998 from 20th Century Average

BASELINE 20TH CENTURY ANNUAL MORBIDITY AND 1998 MORBIDITY FROM NINE DISEASES WITH VACCINES RECOMMENDED BEFORE 1990 FOR UNIVERSAL USE IN CHILDREN: UNITED STATES

Disease	Annual Morbidity	1998 Morbidity	% Decrease

Smallpox	48,164 1	0	100
Diptheria	175,885 2	1	100 3
Pertussis	147,271 4	7,405	95
Tetanus	1,314 5	41	97
Poliomyelitis	16,316 6	1	100 3
Measels	503,282 7	100	100 3
Mumps	152,209 8	666	>99
Rubella	47,745 9	364	>99
Congenital Rubella Syndrome	823 10	7	>99
Haemophilus influenzae type B	20,000 11	61 12	>99


1 Average number of annual case in 1900-1904.
2 Average number of annual case in 1920-1922, 3 years before vaccine development.
3 Rounded to nearest tenth.
4 Average number of annual case in 1922-1925, 4 years before vaccince development.
5 Estimated number of cases based on reported number of deaths during 1922-1926 assuming a case-fatality rate of 90%. 6 Average number of annual case in 1951-1954, 4 years before vaccince licensure. 7 Average number of annual case in 1958-1962, 5 years before vaccince licensure. 8 Number of reported cases in 1968, the first year of reporting began adb the first year after vaccine licensure. 9 Average number of annual case in 1966-1968, 3 years before vaccince licensure. 10 Estimated number of cases based on seroprevalence data in the population and on the risk that women infected during childbearing year would have a fetus with congenital rubella syndrome. 11 Estiamted number of cases from population-based surveillance studies before vaccine licensure in 1985. 12. Excludes 194 cases of Haemophilus influenzae disease of unknown serotype or not type b. Represents unvasive diease in children younger than 5 years of age. Source:MMWR.2000;48(RR-12):8.

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